Simran (Mallika Sherawat), starts having an extra – marital relationship with her ex – boyfriend Sunny (Emraan Hashmi). Simran's husband Sudhir Sehgal (Ashmit Patel) starts doubting his wife and keeps a detective behind her. Thus, it is revealed to Sudhir that Simran is having an affair whereas Simran learns that Sunny is a womanizer and has a girlfriend named Radhika.
Sudhir goes and kills Sunny and buries his body. Radhika files a complaint in the police station about her missing boyfriend. Few days later, Sudhir keeps getting some picture of him resembling that he had buried Sunny's body. Also, he finds that the body goes missing.
In a sudden change of events, Sunny is shown to be alive. It is revealed that the entire situation, from initiating the affair to goading Sudhir into a fight was planned in advance by Sunny, with the help of Radhika. Sunny hoped to have Sudhir imprisoned so that he could continue his affair with Simran. Sunny isolates Simran and chases her into a jungle, where Sudhir arrives and the two begin to fight. Sudhir manages to beat him, and Sunny leaves as he sees the couple together, seemingly realizing their love for each other. However, Sunny then runs up behind Sudhir with a shovel but is then shot in the back by a police officer, who arrives just in time. The couple reunites with the love developed on the strong foundations of the test of mutual support and understanding to lead a happily married life.
Arjun Bhagwat (Emraan Hashmi) is a money-hungry ex-police officer involved in crime. An atheist (nastik), he regularly visits church to donate money to orphans. Priya (Jacqueline Fernandez), a model, is in a passionate but confused relationship with Arjun. Priya is in love with Arjun, who lusts after her. At the beginning of the film, he forces upon her but the relationship continues.
Arjun makes a deal with a gangster and pimp, Sameer, in order to solve the mystery of unexplained disappearance of his prostitutes. While investigating, Arjun finds a phone number linked to the missing girls. He tells Sameer to send a prostitute to the number. Sameer decides to send Reshma (Sulagna Panigrahi), a 17-year-old college newcomer in the business, who has entered prostitution to feed her family, though keeps this a secret from them. Reshma is sent to the house of Dheeraj Pandey (Prashant Narayanan), who is actually a psychopathic murderer responsible for torturing and killing the missing hookers. He decides to do the same with Reshma and throws her in a dark well, with the intention of torturing her till she dies.
Arjun finds out that Dheeraj is the murderer and tells the police. While Dheeraj is held in jail, the commissioner calls a psychiatrist to extract his confession. Dheeraj tells the doctor that he kills women because he thinks they take advantage of men. He also reveals that he castrated himself and became a eunuch to get rid of his sex addiction, with the help of a fellow eunuch and big-shot politician, Nirmala Pandit. Dheeraj is eventually let out under Nirmala Pandit's influence. Meanwhile, Reshma escapes from the well and tries to find her way out through the forest.
Arjun meets Dheeraj's family, who reveal that Dheeraj used to beat his wife. He next meets a private dancer, Sonia, who had also been tortured by Dheeraj, but managed to escape. Arjun then meets an idol-maker who used to work with Dheeraj. The maker tells him that Dheeraj used to make idols of devils instead of deities and killed the factory-owner who tried to stop him. Inspector Sadaa (Sudhanshu Pandey) informs Arjun that Dheeraj is free, and the police try to track him down as quickly as possible. Nirmala and Dheeraj enter the same temple where Reshma is hiding. Nirmala and the priest, who had both been unaware of Dheeraj's true nature, are killed by Dheeraj, but not before the priest reveals that Reshma is there. Dheeraj finds the terrified Reshma and brutally murders her, escaping just before Arjun and the cops arrive. Arjun finds Reshma's body and breaks down, feeling guilty and responsible for her death.
Dheeraj targets Priya next whom he calls for a photoshoot and tries to torture, but Arjun saves her, engaging Dheeraj in a fight as police officers show up. They request Arjun not to kill Dheeraj. Dheeraj then plays the tape he recorded when he was torturing Reshma. Hearing Reshma's pleading cries, Arjun, tormented by her death and blaming himself for it, furiously kills Dheeraj, ending his reign of terror once and for all. As the film ends, Arjun visits a church with Priya, implying that he had a faith in god and Priya's near death has made him realize his love for her.
The film opens with Vikram (Randeep Hooda), a hot-shot fashion and wildlife photographer, viewing a video of his girlfriend, Roshni (Aditi Rao Hydari) telling him she is leaving him. Vikram becomes distraught. While drinking away his sorrows at a bar, he meets Nisha (Sara Loren) and they have a relationship where Nisha moves into the house that Vikram was sharing with Roshni. Vikram becomes a suspect in the disappearance of Roshni, however, the investigators can find no evidence of Vikram's involvement in Roshni's disappearance.
It is revealed that the house is owned by a German lady who shows Roshni a secret room built to hide her husband just in case someone came to look for him because he was in British Army at the time of 1947. The room is self-contained
In a flashback, it is also shown that Roshni, jealous of Vikram's relationship with one of his colleague, decided to pretend she is leaving him. She creates the video saying she is leaving as she hides in the secret room. The room has some one way mirrors where she can observe Vikram's reaction. When she decides he has had enough she looks for the key and realizes she lost the key and is now trapped in the room with no way to contact him.
Nisha finds the key to the secret room, but she doesn't know what it is used for. Also, Nisha finds something spooky in the house. However, after few days she gets to know that Roshni is alive and is being trapped inside the secret room. But, Nisha doesn't help her as she didn't want to lose Vikram. Nisha gets curious and opens the door and finds Roshni sleeping, wherein she hits a glass bottle on Nisha's head making her unconscious. Roshni elopes away from there and locks Nisha in the secret room. Thus, the police find Nisha disappeared and eventually arrest Vikram.
The film ends with Roshni tearing the photograph of her and Vikram and goes far away from there.Mallika Sherawat as Simran Sehgal
Emraan Hashmi as Sunny
Ashmit Patel as Sudhir Sehgal
Raj Zutshi as Inspector Rajvir Singh.
Emraan Hashmi as Arjun Bhagawat
Jacqueline Fernandez as Priya
Prashant Narayanan as Dheeraj Pandey
Sulagna Panigrahi as Reshma.
Randeep Hooda as Vikram
Aditi Rao Hydari as Roshni
Sara Loren as Nisha
Rajesh Shringarpure as Kabir.
The first Murder was an uncredited remake of 2002 Hollywood film Unfaithful. Murder 2 was an uncredited remake of South Korean film The Chaser (film). Murder 3 was an official remake of the Colombian thriller The Hidden Face.