The midaidokoro (御台所) was the official wife of the Shogun. During the Edo period, she resided in the Ōoku of Edo Castle and sometimes wielded considerable political power behind the scenes. This title first use by Oeyo wife of second shogun, Tokugawa Hidetada.
List of Midaidokoro:
Oeyo, wife of Tokugawa Hidetada and mother of Tokugawa IemitsuTakatsukasa Takako (1622-1683), wife of Tokugawa Iemitsu and daughter of Takatsukasa Nobufusa, grandmother of Tokugawa Ienobu, great grandmother of Tokugawa IetsuguAsa no Miya Akiko (1640-1676), wife of Tokugawa Ietsuna and daughter of Fushimi no Miya SadakiyoTakatsukasa Nobuko (1651-1709) ,wife of Tokugawa Tsunayoshi and daughter of Takatsukasa NorihiraKonoe Hiroko (1666-1741) later Ten-ei'in, wife of Tokugawa Ienobu and daughter of Konoe MotohiroYoshiko no Miya (1714-1758), wife of Tokugawa Ietsugu and daughter of Emperor ReigenIso no Miya Tomoko (1738-1771), wife of Tokugawa Ieharu and daughter of Kan'in no Miya Naohito ShinnoShimazu no Shigehime or Tadakohime (1773-1844) later Kodai-in, wife of Tokugawa Ienari and daughter of Shimazu Shigehide of Satsuma DomainArisugawa Takako (1795-1840) later Jokan-in, wife of Tokugawa Ieyoshi and daughter of Prince Arisugawa OrihitoShimazu Atsuhime or Fujiwara no Sumiko, later Tenshoin, wife of Tokugawa Iesada and daughter of Shimazu Tadatake (1806-1854) ,adopted daughter of Shimazu Nariakira and Konoe TadahiroChikako, Princess Kazu, later Seikan'in-no-miya, wife of Tokugawa Iemochi and daughter of Emperor NinkoIchijo Mikako (1835-1894), wife of Tokugawa Yoshinobu