Initial release 2000 Written in C++ | Stable release 4.9.1 / 2016 | |
Original author(s) Developer(s) Daniel E. Weeks, Robert V. Baron, Justin R. Stickel. Operating system | ||
Mega2, the Manipulation Environment for Genetic Analysis, allows the applied statistical geneticist to convert one's data from several input formats to a large number output formats suitable for analysis by commonly used software packages. In a typical human genetics study, the analyst often needs to use a variety of different software programs to analyze the data, and these programs usually require that the data be formatted to their precise input specifications. Conversion of one's data into these multiple different formats can be tedious, time-consuming, and error-prone. Mega2, by providing validated conversion pipelines, can accelerate the analyses while reducing errors.
Contents
Mega2 has been used to facilitate genetic analyses of a wide variety of human traits, including hereditary dystonia, Ehlers-Danlos syndrome, multiple sclerosis, and gliomas. A list of PubMed Central articles citing Mega2 can be seen here.
Mega2, which focusses on data reformatting, should not be confused with the MEGA, Molecular Evolutionary Genetics Analysis program, which focuses on molecular evolution and phylogenetics.
Input file formats
Mega2 accepts input data in a variety of widely used file formats. These contain, at a minimum, data about the phenotypes, the marker genotypes, any family structures, and map positions of the markers.
Output file formats
Mega2 supports conversion to the following output formats.
Mega2 documentation
The Mega2 documentation is available here in HTML format, and here in PDF format.