Girish Mahajan (Editor)

Magaldrate

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MedlinePlus
  
a682683

Routes of administration
  
Oral

Molar mass
  
212.66 g/mol

Pregnancy category
  
C

CAS ID
  
1317-26-6

AHFS/Drugs.com
  
Micromedex Detailed Consumer Information

ATC code
  
A02AD02 (WHO) A02AF01 (WHO) (combination with antiflatulents)

Legal status
  
In general: Over-the-counter (OTC)

Magaldrate (INN) is a common antacid drug that is used for the treatment of duodenal and gastric ulcers, esophagitis from gastroesophageal reflux.

Contents

Available forms

Magaldrate is available in the form of oral suspension or tablets.

Pharmacology

Magaldrate is a hydroxymagnesium aluminate complex that is converted rapidly in gastric acid to Mg(OH)2 and Al(OH)3, which are absorbed poorly and thus provide a sustained antacid effect.

Interactions and adverse reactions

Magaldrate may negatively influence drugs like tetracyclines, benzodiazepines, and indomethacin. High doses or prolonged usage may lead to an increment of defecation and a reduction in feces consistence. In some cases it can alter the functionality of the gastrointestinal tract, occasionally provoking constipation or diarrhea.

References

Magaldrate Wikipedia