Species Human Entrez 8649 | Human Mouse Ensembl ENSG00000109270 | |
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Aliases LAMTOR3, MAP2K1IP1, MAPBP, MAPKSP1, MP1, PRO0633, Ragulator3, late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 External IDs MGI: 1929467 HomoloGene: 10539 GeneCards: LAMTOR3 | ||
Mitogen-activated protein kinase scaffold protein 1 is a scaffold protein that in humans is encoded by the MAPKSP1 gene.
Contents
Function
The protein encoded by this gene was identified as an interacting protein that binds specifically to MAP kinase kinase MAP2K1/MEK1 and to MAP kinase MAPK2/ERK1. This protein enhances the activation of MAPK2, and thus is thought to function as an adaptor to enhance the efficiency of the MAP kinase cascade.
Interactions
MAP2K1IP1 has been shown to interact with MAP2K1.
References
MAP2K1IP1 Wikipedia(Text) CC BY-SA