Puneet Varma (Editor)

MAD2L2

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Species
  
Human

Entrez
  
10459

Human
  
Mouse

Ensembl
  
ENSG00000116670

MAD2L2

Aliases
  
MAD2L2, MAD2B, POLZ2, REV7, MAD2 mitotic arrest deficient-like 2 (yeast)

External IDs
  
MGI: 1919140 HomoloGene: 4624 GeneCards: MAD2L2

Mitotic spindle assembly checkpoint protein MAD2B is a protein that in humans is encoded by the MAD2L2 gene.

Contents

Function

MAD2L2 is a component of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. MAD2L2 is a homolog of MAD2L1.

Interactions

MAD2L2 has been shown to interact with:

  • ADAM9,
  • MAD2L1,
  • REV1, and
  • REV3L.
  • References

    MAD2L2 Wikipedia