Entrez 8754 | Ensembl n/a | |
Aliases ADAM9, CORD9, MCMP, MDC9, Mltng, ADAM metallopeptidase domain 9 External IDs MGI: 105376 HomoloGene: 20824 GeneCards: ADAM9 | ||
Disintegrin and metalloproteinase domain-containing protein 9 is an enzyme that in humans is encoded by the ADAM9 gene.
Contents
Function
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene interacts with SH3 domain-containing proteins, binds mitotic arrest deficient 2 beta protein, and is also involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor. Two alternative splice variants have been identified, encoding distinct isoforms.
Interactions
ADAM9 has been shown to interact with: