Species Human Entrez 9170 | Human Mouse Ensembl ENSG00000064547 | |
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Aliases LPAR2, EDG-4, EDG4, LPA-2, LPA2, lysophosphatidic acid receptor 2 External IDs MGI: 1858422 HomoloGene: 3465 GeneCards: LPAR2 | ||
Lysophosphatidic acid receptor 2 also known as LPA2 is a protein that in humans is encoded by the LPAR2 gene. LPA2 is a G protein-coupled receptor that binds the lipid signaling molecule lysophosphatidic acid (LPA).
Contents
Function
This gene encodes a member of family I of the G protein-coupled receptors, as well as the EDG family of proteins. This protein functions as a lysophosphatidic acid (LPA) receptor and contributes to Ca2+ mobilization, a critical cellular response to LPA in cells, through association with Gi and Gq proteins.
Interactions
LPAR2 has been shown to interact with TRIP6.
References
LPAR2 Wikipedia(Text) CC BY-SA