Entrez 3861 | Ensembl ENSG00000186847 | |
Aliases KRT14, CK14, EBS3, EBS4, K14, NFJ, keratin 14 External IDs OMIM: 148066 MGI: 96688 HomoloGene: 110439 GeneCards: KRT14 | ||
Complementary roles of specific cysteines in keratin 14 towards the assembly organization
Keratin 14 is a member of the type I keratin family of intermediate filament proteins. Keratin 14 was the first type I keratin sequence determined. Keratin 14 is also known as cytokeratin-14 (CK-14) or keratin-14 (KRT14). In humans it is encoded by the KRT14 gene.
Contents
- Complementary roles of specific cysteines in keratin 14 towards the assembly organization
- Gene music using protein sequence of krt14 keratin 14 type i
- Pathology
- References
Keratin 14 is usually found as a heterodimer with type II keratin 5 and form the cytoskeleton of epithelial cells.
Gene music using protein sequence of krt14 keratin 14 type i
Pathology
Mutations in the genes for these keratins are associated with epidermolysis bullosa simplex and Dermatopathia pigmentosa reticularis, both of which are autosomal dominant mutations.
References
Keratin 14 Wikipedia(Text) CC BY-SA