Puneet Varma (Editor)

Keratin 10

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Species  Human
Entrez  3858
Human  Mouse
Ensembl  ENSG00000186395
Keratin 10

Aliases  KRT10, BCIE, BIE, CK10, EHK, K10, KPP, keratin 10
External IDs  OMIM: 148080 HomoloGene: 20125 GeneCards: KRT10

Keratin, type I cytoskeletal 10 also known as cytokeratin-10 (CK-10) or keratin-10 (K10) is a protein that in humans is encoded by the KRT10 gene. Keratin 10 is a type I keratin.



Keratin-10 is a member of the type I (acidic) cytokeratin family, which belongs to the superfamily of intermediate filament (IF) proteins. Keratins are heteropolymeric structural proteins which form the intermediate filament. These filaments, along with actin microfilaments and microtubules, compose the cytoskeleton of epithelial cells. Mutations in this gene are associated with epidermolytic hyperkeratosis. This gene is located within a cluster of keratin family members on chromosome 17q21.


Keratin 10 has been shown to interact with AKT1.


Keratin 10 Wikipedia