Entrez 57576 | Ensembl ENSG00000117245 | |
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Aliases KIF17, Kif17, 5930435E01Rik, AW492270, Kif17b, mKIAA1405, KIF3X, KLP-2, OSM-3, kinesin family member 17 External IDs MGI: 1098229 HomoloGene: 5883 GeneCards: KIF17 |
Kinesin-like protein KIF17 is a protein that in humans is encoded by the KIF17 gene. KIF17 and its close relative, C. elegans OSM-3, are members of the kinesin-2 family of plus-end directed microtubule-based motor proteins. In contrast to heterotrimeric kinesin-2 motors, however, KIF17 and OSM-3 form distinct homodimeric complexes. Homodimeric kinesin-2 has been implicated in the transport of NMDA receptors along dendrites for delivery to the dendritic membrane, whereas both heterotrimeric and homodimeric kinesin-2 motors function cooperatively in anterograde intraflagellar transport (IFT) and cilium biogenesis.
References
KIF17 Wikipedia(Text) CC BY-SA