Profession Doctor Died 1967 | Name Janet Lane-Claypon Role Physician | |
 | ||
Born 1877 Lincolnshire | ||
Education University College London | ||
Janet Elizabeth Lane-Claypon, Lady Forber (3 February 1877 – 17 July 1967) was an English physician. She was one of the founders of the science of epidemiology, pioneering the use of cohort studies and case-control studies.
Contents
Early life and education
Lane-Claypon was born Janet Elizabeth Claypon in 1877 into an affluent family, in Boston, Lincolnshire, the daughter of William Ward Lane-Claypon, a banker and former first-class cricketer, and Edith (née Stow). Her uncle C. G. Lane was also a first-class cricketer. A few weeks after her birth, her father changed the family name to Lane-Claypon by royal licence.
She was privately educated and entered the London School of Medicine for Women in 1898. She won various honours and fellowships. She earned both an MD and PhD (making her an early example of the "Doctor-doctor" phenomenon).
Career
In 1912, Lane-Claypon published a ground-breaking study of two cohorts (groups) of babies, fed cow's milk and breast milk respectively. Lane-Claypon found that those babies fed breast milk gained more weight, and she used statistical methods to show that the difference was unlikely to occur by fluke alone. She also investigated whether something other than the type of milk could account for the difference, an effect known as confounding.
Having demonstrated the power of cohort studies, Lane-Claypon went on to develop another key type of epidemiological investigation, the case-control study.
Lane-Claypon tracked down 500 women with a history of breast cancer – the "cases" – and compared them with 500 women who were free of the disease but otherwise broadly similar, known as "controls".
She showed that breast cancer risk increased for childless women, women who married later than average, and women who did not breast feed. The overall breast cancer risk decreased according to the number of children. For all cases, rapid treatment held the key to survival among women with breast cancer.
Personal life
In 1929, Lane-Claypon married civil servant Sir Edward Rodolph Forber (1878–1960), as his second wife. Forber held several prominent positions, including Deputy Secretary of the Ministry of Health. Lane-Claypon's final paper was published under her married name, and she essentially retired following her marriage, not uncommon for a woman of her class in this era.
Lady Forber died in 1967, aged 90.