Harman Patil (Editor)

J147

Updated on
Edit
Like
Comment
Share on FacebookTweet on TwitterShare on LinkedInShare on Reddit
CAS Number
  
1146963-51-0

ChemSpider
  
29341612

Molar mass
  
350.34 gĀ·mol

PubChem CID
  
25229652

Formula
  
C18H17F3N2O2

J147 s9postimgorgj0m40lp4fjournalpone0027865g001

Legal status
  
US: Investigational New Drug

New alzheimer s drug shows anti aging powers j147


J147 is an experimental drug with reported effects against both Alzheimer's disease and ageing in mouse models of accelerated aging.

Contents

The approach that lead to development of the J147 drug was to screen candidate molecules for anti-aging effects, instead of targeting the amyloid plaques. It is contrary to most other approaches to developing drugs against Alzheimer's disease that target the plaque deposits in the brain.

The J147 drug is also reported to address other biological aging factors, such as preventing the leakage of blood from microvessels in mice brains. The development of J147 follows the chemical pharmacological way, contrary to biological ways that exploit e.g. use of bacteriophages.

Lack of toxicity in preclinical alzheimer s drug j147


References

J147 Wikipedia