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Isocitrate dehydrogenase (NADP ) kinase

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EC number
  
2.7.11.5

IntEnz
  
IntEnz view

ExPASy
  
NiceZyme view

CAS number
  
83682-93-3

BRENDA
  
BRENDA entry

KEGG
  
KEGG entry

In enzymology, a [isocitrate dehydrogenase (NADP+)] kinase (EC 2.7.11.5) is an enzyme that catalyzes the chemical reaction:

ATP + [isocitrate dehydrogenase (NADP+)] ADP + [isocitrate dehydrogenase (NADP+)] phosphate

Thus, the two substrates of this enzyme are ATP and isocitrate dehydrogenase (NADP+), whereas its two products are ADP and isocitrate dehydrogenase (NADP+) phosphate.

This enzyme belongs to the family of transferases, specifically those transferring a phosphate group to the sidechain oxygen atom of serine or threonine residues in proteins (protein-serine/threonine kinases).

Other names

The systematic name of this enzyme class is ATP:[isocitrate dehydrogenase (NADP+)] phosphotransferase. Other names in common use include [isocitrate dehydrogenase (NADP+)] kinase, ICDH kinase/phosphatase, IDH kinase, IDH kinase/phosphatase, IDH-K/P, IDHK/P, isocitrate dehydrogenase kinase (phosphorylating), isocitrate dehydrogenase kinase/phosphatase, and STK3.

References

Isocitrate dehydrogenase (NADP+) kinase Wikipedia


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