She began her career as a model at age 11 and 15 she became a professional model. Two years later, at the insistence of her agency, Ford Models, took the test and marked his acting debut in the role of "Ritinha" in Renascer the soap opera, aired by TV Globo. participated, along with two other members of the group Sublime, who made ephemeral success in the 1990s. In November 1996 she posed nude for Playboy magazine.
Isabel has starred in several novels like A Lua Me Disse, Começar de Novo, A Padroeira, Força de um Desejo, Corpo Dourado, A Indomada, O Fim do Mundo, A Próxima Vítima and Pátria Minha.
In the film, Isabel appeared in Orfeu, Navalha na Carne and O Homem Nu.
In 2007, Elizabeth joined the cast of the novel Sete Pecados, Walcyr Carrasco, and in 2008 he joined the cast of the television series Malhação.
The actress, in 2011, made a cameo in the last chapter of the soap opera Insensato Coração, currently plays the lawyer Mônica Fina Estampa in the novel.
She is currently single, but had previously married to engineer Júlio César Santos and mother of Analuz, Isabel was pregnant with her second son, Jamal Anuar, and two months after the birth of the child, discovered that he was a carrier of West syndrome, a type epilepsy that alters the development of mind. Stirred, decided to plead the cause of disease carriers, and in 2006 launched the forces of good, dedicated to promoting assistance to persons who require special care (blind, mental, hearing and / or engines) and who are unable to do so.
In 2003 she had founded the NGO Donate Your Junk, focused on socio-environmental area. On December 28, 2013, the actress gave birth to her third son, Kalel.