Group Group I (dsDNA) Family Herpesviridae Higher classification Herpesviruses | Order Herpesvirales Subfamily Alphaherpesvirinae Rank Genus | |
Similar Alphaherpesvirinae, Gallid herpesvir, Varicellovirus, Herpesvirales, Lymphocryptovirus | ||
Iltovirus is a genus of viruses in the order Herpesvirales, in the family Herpesviridae, in the subfamily Alphaherpesvirinae. Birds, galliform birds, psittacine birds, chickens, turkeys, and quail serve as natural hosts. There are currently only two species in this genus including the type species Gallid herpesvirus 1. Diseases associated with this genus include: acute respiratory diseases: gaHV-1: infectious laryngotracheitis; psHV-1: Pacheco's disease.
Contents
Taxonomy
Group: dsDNA
Structure
Viruses in Iltovirus are enveloped, with icosahedral, Spherical to pleomorphic, and Round geometries, and T=16 symmetry. The diameter is around 120-200 nm. Genomes are linear and non-segmented, around 150kb in length.
Life Cycle
Viral replication is nuclear, and is lysogenic. Entry into the host cell is achieved by attachment of the viral gB, gC, gD and gH proteins to host receptors, which mediates endocytosis. Replication follows the dsDNA bidirectional replication model. DNA-templated transcription, with some alternative splicing mechanism is the method of transcription. The virus exits the host cell by nuclear egress, and budding. Birds, galliform birds, psittacine birds, chickens, turkeys, and quail serve as the natural host. Transmission routes are contact, contamination, and air borne particles.