Entrez 8100 | Ensembl ENSG00000032742 | |
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Aliases IFT88, D13S1056E, DAF19, TG737, TTC10, hTg737, intraflagellar transport 88 External IDs MGI: 98715 HomoloGene: 4761 GeneCards: IFT88 | ||
Intraflagellar transport protein 88 homolog is a protein that in humans is encoded by the IFT88 gene.
Contents
Function
This gene encodes a member of the tetratrico peptide repeat (TPR) family. Mutations of a similar gene in mouse can cause polycystic kidney disease. Two transcript variants encoding distinct isoforms have been identified for this gene. In 2012 a mutation was found to be responsible for a novel form of ciliopathy and anosmia in humans capable of remedy in mice by adenoviral mediated gene therapy.
Interactions
IFT88 has been shown to interact with BAT2.
References
IFT88 Wikipedia(Text) CC BY-SA