Neha Patil (Editor)

BAT2

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Species
  
Human

Entrez
  
7916

Human
  
Mouse

Ensembl
  
n/a

BAT2

Aliases
  
PRRC2A, BAT2, D6S51, D6S51E, G2, proline rich coiled-coil 2A

External IDs
  
MGI: 1915467 HomoloGene: 10567 GeneCards: PRRC2A

Large proline-rich protein BAT2 is a protein that in humans is encoded by the BAT2 gene.

Contents

Function

A cluster of genes, BAT1-BAT5, has been localized in the vicinity of the genes for TNF alpha and TNF beta. These genes are all within the human major histocompatibility complex class III region. This gene has microsatellite repeats which are associated with the age-at-onset of insulin-dependent diabetes mellitus (IDDM) and possibly thought to be involved with the inflammatory process of pancreatic beta-cell destruction during the development of IDDM. This gene is also a candidate gene for the development of rheumatoid arthritis. There are two alternatively spliced transcripts encoding different isoforms described for this gene.

Interactions

BAT2 has been shown to interact with:

  • C1QBP,
  • EIF3S6,
  • HNRNPA1,
  • IFT88,
  • IMMT, and
  • UBAP2L.

    • References

    BAT2 Wikipedia
    (Text) CC BY-SA


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