Species Human Entrez 3455 | Human Mouse Ensembl ENSG00000159110 | |
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Aliases IFNAR2, IFN-R, IFN-alpha-REC, IFNABR, IFNARB, IMD45, interferon alpha and beta receptor subunit 2 External IDs MGI: 1098243 HomoloGene: 49242 GeneCards: IFNAR2 | ||
Interferon-alpha/beta receptor beta chain is a protein that in humans is encoded by the IFNAR2 gene.
Contents
Function
The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. Multiple transcript variants encoding at least two different isoforms have been found for this gene.
Interactions
IFNAR2 has been shown to interact with:
References
IFNAR2 Wikipedia(Text) CC BY-SA