Species Human Entrez 3454 | Human Mouse Ensembl ENSG00000142166 | |
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Aliases IFNAR1, AVP, IFN-alpha-REC, IFNAR, IFNBR, IFRC, interferon alpha and beta receptor subunit 1 External IDs MGI: 107658 HomoloGene: 524 GeneCards: IFNAR1 | ||
Interferon-alpha/beta receptor alpha chain is a protein that in humans is encoded by the IFNAR1 gene.
Contents
Function
The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. The encoded protein also functions as an antiviral factor.
Interactions
IFNAR1 has been shown to interact with:
References
IFNAR1 Wikipedia(Text) CC BY-SA