Hofstadter is a surname. Notable people with the surname include:
Albert Hofstadter (1910–1989), American philosopher
Douglas Hofstadter (born 1945), American professor, author of Gödel, Escher, Bach
Richard Hofstadter (1916–1970), American historian
Robert Hofstadter (1915–1990), American Nobel Prize-winner in physics
Samuel H. Hofstadter (1894–1970), New York politician and judge
Fictional characters:
Leonard Hofstadter, a character in the television series The Big Bang Theory