Species Human Entrez 3066 | Human Mouse Ensembl ENSG00000196591 | |
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Aliases HDAC2, HD2, RPD3, YAF1, histone deacetylase 2 External IDs MGI: 1097691 HomoloGene: 68187 GeneCards: HDAC2 | ||
Histone deacetylase 2 (HDAC2) is an enzyme that in humans is encoded by the HDAC2 gene.
Contents
Function
This gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes and are responsible for the deacetylation of lysine residues on the N-terminal region of the core histones (H2A, H2B, H3 and H4). This protein also forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus it plays an important role in transcriptional regulation, cell cycle progression and developmental events.
Interactions
Histone deacetylase 2 has been shown to interact with:
References
Histone deacetylase 2 Wikipedia(Text) CC BY-SA