Supriya Ghosh (Editor)

Hepatotoxin

Updated on
Edit
Like
Comment
Share on FacebookTweet on TwitterShare on LinkedInShare on Reddit

A hepatotoxin (Gr., hepato = liver) is a toxic chemical substance that damages the liver.

It can be a side-effect of medication, or found naturally, as microcystins, or in laboratory environments.

The effects of hepatotoxins depend on the amount, point of entry and distribution speed of the toxin, and on the health of the person.

Hepatotoxic substances

  • α-amanitin, a deadly cellular toxin found in Amanita phalloides mushroom (death cap)
  • Aflatoxin
  • Halothane
  • Carbon tetrachloride
  • Pyrrolizidine alkaloids, found in many plants in the Boraginaceae, Compositae, and Leguminosae families.
  • Luteoskyrin
  • allyl alcohol, amiodarone, Aroclor 1254, arsenic, carbamazepine, carbon tetrachloride, diethylnitrosamine, dimethylformamide, diquat, etoposide, indomethacin, methapyrilene, methotrexate, monocrotaline, and 3-methylcholanthrene.

    • References

    Hepatotoxin Wikipedia
    (Text) CC BY-SA