Haemodialysis associated amyloidosis

Presentation

Long-term haemodialysis results in a gradual accumulation of β₂ microglobulin, a serum protein, in the blood. It accumulates because it is unable to cross the dialysis filter.

Affected individuals usually present after 5 years of dialysis rarely before that. The tendency of haemodialysis-associated amyloidosis is to be articular in general affecting the joints.

Prevention

Low copper dialysis is theorized to prevent or delay onset.