Frye is a surname. Notable people with the surname include:
Channing Frye (born 1983), basketball playerCharlie Frye (born 1981), football player for the Oakland RaidersDon Frye (born 1965), mixed martial arts fighterDonna Frye (born 1952), San Diego city councilwomanDwight Frye (1899–1943), American actorJack Frye (1904–1959), American aviation pioneerJohn Frye (1933–2005), Scottish footballerJoseph Frye (1712–1794), colonial American soldier and generalMarilyn Frye (born 1941), American philosophy professor and feminist theoristMark Frye (born 1957), contemporary American composerNorthrop Frye (1912–1991), Canadian literary criticRichard Nelson Frye (born 1920?), American scholar of Iranian historySean Frye (born 1966), American child actorSoleil Moon Frye (born 1976), American actress best known for playing Punky BrewsterTaylor Frye (1864–1946), American politician and educatorThomas Frye (c. 1710–1762), Anglo-Irish painterThomas Frye (Rhode Island) (1666–1748), Deputy Governor of colony of Rhode IslandVirgil Frye (1930–2012), American actorWalter Frye (died 1474), English Renaissance composerWilliam P. Frye (1830–1911), U.S. Senator from Maine