| C16H12O4|| 268.26 g/mol|
Formononetin is an O-methylated isoflavone.
Formononetin is found in a number of plants and herbs like the red clover. Along with other phytoestrogens, it predominantly occurs in leguminous plants and Fabaceae, particularly in beans, such as green beans, lima beans, soy and many others, as the free aglycone or in form of its glucoside ononin.
It can also be found in Maackia amurensis cell cultures.
The enzyme 4'-methoxyisoflavone 2'-hydroxylase uses formononetin, NADPH, H+, and O2 to produce 2'-hydroxyformononetin, NADP+ and H2O.
The enzyme Isoflavone 3'-hydroxylase uses formononetin, NADPH, H+, and O2 to produce calycosin (3'-hydroxyformononetin), NADP+ and H2O.
Ononin is the 7-O-glucoside of formononetin.