Fibrolase

Fibrolase (EC 3.4.24.72, fibrinolytic proteinase, Agkistrodon contortrix contortrix metalloproteinase, Agkistrodon contortrix contortrix venom metalloproteinase) is an enzyme. This enzyme catalyses the following chemical reaction

Hydrolysis of -Ala¹⁴-Leu- in insulin B chain and -Lys⁴¹³-Leu- in Aalpha-chain of fibrinogen

This enzyme is present in the venom of the southern copperhead snake (Agkistrodon contortrix contortrix).