Samiksha Jaiswal (Editor)

FNBP1

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Species
  
Entrez
  
23048

Human
  
Ensembl
  
ENSG00000187239

FNBP1

Aliases
  
FNBP1, FBP17, formin binding protein 1

External IDs
  
MGI: 109606 HomoloGene: 100983 GeneCards: FNBP1

Formin-binding protein 1 is a protein that in humans is encoded by the FNBP1 gene.

Contents

Function

The protein encoded by this gene is a member of the formin-binding-protein family. The protein contains an N-terminal Fer/Cdc42-interacting protein 4 (CIP4) homology (FCH) domain followed by a coiled-coil domain, a proline-rich motif, a second coiled-coil domain, a Rho family protein-binding domain (RBD), and a C-terminal SH3 domain. This protein binds sorting nexin 2 (SNX2), tankyrase (TNKS), and dynamin; an interaction between this protein and formin has not been demonstrated yet in human.

Interactions

FNBP1 has been shown to interact with:

  • AKAP9,
  • DNM1,
  • Fas ligand
  • SNX2, and
  • TNKS.
  • References

    FNBP1 Wikipedia


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