Harman Patil

Etynodiol

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ATC code  G03DC06 (WHO)
PubChem CID  14687
ECHA InfoCard  100.013.610
Molar mass  300.435 g/mol
CAS Number  1231-93-2
ChemSpider  14017
Formula  C20H28O2
Etynodiol httpsuploadwikimediaorgwikipediacommonsthu

Etynodiol (INN), or ethynodiol (BAN), also known as 3β-hydroxynorethisterone, is a steroidal progestin related to norethisterone which was never marketed. A diacylated derivative, etynodiol diacetate, is used as a hormonal contraceptive. While etynodiol is sometimes used as a synonym for etynodiol diacetate, it usually refers to etynodiol diacetate, not etynodiol.

Contents

Pharmacology

Etynodiol is a prodrug of norethisterone, and is converted immediately and completely into norethisterone. In addition, etynodiol is an intermediate in the conversion of the prodrug lynestrenol into norethisterone.

Chemistry

Etynodiol is a 19-nortestosterone derivative. Structurally, it is almost identical to norethisterone and lynestrenol, differing only in its C3 substituent. Whereas norethisterone has a ketone at C3 and lynestrenol has no substituent at C3, etynodiol has a hydroxyl group at the position.

References

Etynodiol Wikipedia


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