ATC code D06BB09 (WHO) PubChem CID 66377 UNII 15ZQM81Y3R | CAS Number 15176-29-1 ChemSpider 59752 ChEMBL CHEMBL318153 | |
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Edoxudine (or edoxudin) is an antiviral drug. It is an analog of thymidine, a nucleoside.
It has shown effectiveness against herpes simplex virus.
Synthesis
Mercuration of the 2'-deoxyuridine 1 leads to the organometallic derivative 2; reaction of that with ethylene in the presence dilithiopalladium tetrachloride gives the alkylation product 3; this is reduced catalytically in situ. There is thus obtained the antiviral agent edoxudine 4.
References
Edoxudine Wikipedia(Text) CC BY-SA