ESCAPPM or ESCHAPPM is a mnemonic for the organisms with inducible beta-lactamase activity that is chromosomally mediated.
In vitro sensitivities are not applicable in vivo.
In general, treatment with cephalosporins results in inducible beta-lactamase activity. Treatment with an aminoglycoside or carbapenem is usually indicated. Carbapenems are a class of beta-lactam antibiotics with a broad spectrum of antibacterial activity. They have a structure that renders them highly resistant to beta-lactamases. Examples of Carbapenems include meropenem and imipenem.
References
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