Harman Patil (Editor)

ELK4

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Species
  
Human

Entrez
  
2005

Human
  
Mouse

Ensembl
  
ENSG00000158711

ELK4

Aliases
  
ELK4, SAP1, ETS transcription factor

External IDs
  
MGI: 102853 HomoloGene: 1492 GeneCards: ELK4

ETS domain-containing protein Elk-4 is a protein that in humans is encoded by the ELK4 gene.

Contents

Function

This gene is a member of the Ets family of transcription factors and of the ternary complex factor (TCF) subfamily. Proteins of the TCF subfamily form a ternary complex by binding to the serum response factor and the serum response element in the promoter of the c-fos proto-oncogene. The protein encoded by this gene is phosphorylated by the kinases, MAPK1 and MAPK8. Several transcript variants have been described for this gene.

Interactions

ELK4 has been shown to interact with:

  • BRCA1, and
  • Serum response factor
  • References

    ELK4 Wikipedia