Species Human Entrez 1984 | Human Mouse Ensembl ENSG00000132507 | |
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Aliases EIF5A, EIF-5A, EIF5A1, eIF5AI, eukaryotic translation initiation factor 5A External IDs MGI: 106248 HomoloGene: 133803 GeneCards: EIF5A | ||
Gene music using protein sequence of eif5a eukaryotic translation initiation factor 5a
Eukaryotic translation initiation factor 5A-1 is a protein that in humans is encoded by the EIF5A gene.
It is the only known protein to contain the unusual amino acid hypusine [N (ε)- (4-amino-2-hydroxybutyl)-lysine], which is synthesized on eIF5A at a specific lysine residue from the polyamine spermidine by two catalytic steps.
EF-P is the prokaryotic homolog of eIF5A, which is also modified post-translationally in a similar but distinct way.
References
EIF5A Wikipedia(Text) CC BY-SA