Abbreviations DIPA Density 717 kg/m³ | Appearance Colorless liquid Formula C6H15N | |
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Related amines Related compounds | ||
Diisopropylamine is a secondary amine with the chemical formula (CH3)2HC-NH-CH(CH3)2. It is best known as its lithium derivative of its conjugate base, lithium diisopropylamide, known as "LDA". LDA is a strong, non-nucleophilic base.
Contents
Diisopropylamine can be dried by distillation from potassium hydroxide (KOH) or drying over sodium wire.
Reactions and uses
Diisopropylamine is primarily used as a precursor to two herbicides, diallate and triallate, as well as certain sulfenamides used in the vulcanization of rubber. It is also used to prepare N,N-Diisopropylethylamine (Hünig's base) by alkylation with diethyl sulfate.
The bromide salt of diisopropylamine, diisopropylammonium bromide, is an organic molecular solid whose crystals are ferroelectric at room temperature. This renders it a possible more biospherically inert alternative to barium titanate.
Preparation
Diisopropylamine is commercially available. It may be prepared by the reductive amination of acetone with ammonia using a modified copper oxide, generally copper chromite, as a catalyst:
NH3 + 2(CH
3)
2CO + 2H
2 → C
6H
15N + 2H
2O