Trisha Shetty (Editor)

Diethyl sulfate

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Density
  
1.2 g/cm³

Appearance
  
Colorless liquid

Diethyl sulfate wwwsigmaaldrichcomcontentdamsigmaaldrichstr

Related compounds
  
Dimethyl sulfate; diethyl sulfite

Diethyl sulfate is a highly toxic and likely carcinogenic chemical compound with formula (C2H5)2SO4. It occurs as a colorless, oily liquid with a faint peppermint odor and is corrosive.

Contents

Diethyl sulfate is used as an alkylating agent to prepare ethyl derivatives of phenols, amines, and thiols. It is used to manufacture dyes and textiles.

Toxicity

Diethyl sulfate is a strong alkylating agent which ethylates DNA and thus is genotoxic. There is not sufficient evidence for the carcinogenic properties of diethyl sulfate in humans, but there is in animals. It is classified as a Group 2A carcinogen by the IARC

Preparation

It can be prepared by absorbing ethylene into concentrated sulfuric acid or by fuming sulfuric acid into diethyl ether or ethanol.

References

Diethyl sulfate Wikipedia