Born on August 21, 1987 to LaShelle Bonner and Sean Floyd, she has three siblings, sister Vin'Centia Dewberry, brother Justin McCall, and sister Erica McCall. Bonner majored in Psychology at Auburn University. In November 2016 Bonner married fellow WNBA player (and former Mercury teammate) Candice Dupree. In March 2017 it was confirmed Bonner was expecting the couple's first child and will miss the 2017 WNBA season. Bonner and Dupree welcomed twin daughters on July 30, 2017.
Bonner attended high school at Fairfield High School in Fairfield, Alabama. She was named McDonald's and WBCA All-American and participated in their All-America games. She earned USA Today Junior All-America and was the Gatorade Alabama Player of the Year while at Fairfield High School. She was featured in USA Today as one of the top 25 recruits in the nation during summer of 2005.
Bonner went to Auburn University, where she earned a degree in psychology. She was named to the SEC All-Freshman Team. She scored in double figures in 22 games during the 2005–06 season and led the Tigers with a 13.5 points per game average, the first time since 1980–81 that a freshman led the team in scoring.
This led Bonner to join the youth teams of US basketball, winning the 2006 FIBA Americas Under-20 Championship for Women and the FIBA Under-21 World Championship for Women one year later.
Bonner went on to put together one of the most impressive careers ever at Auburn. The 2009 SEC Player of the Year and a National Player of the Year finalist, she broke the Auburn career scoring record during the Ole Miss game at the SEC Tournament. She finished her career with 2,162 points, nearly 100 more than the former school record.
She also finished her career as one of Auburn's top rebounders, taking second all-time with 1,047 rebounds, placing her among three Tigers to ever finish their career with more than 2,000 points and 1,000 rebounds. Listed in the top 10 in every major statistical category at Auburn, she also ranks sixth in blocks, seventh in steals, first in free throws, fourth in field goals and 10th in 3-pointers.
Bonner led the SEC in scoring that season, becoming the first Auburn player to ever earn the honor. She also ranked 10th in the country in scoring while setting the Auburn single-season scoring record with 716 points, 21.1 per game.
She went on to earn WBCA/State Farm, USBWA, AP and ESPN.com All-America honors and was voted the Alabama Sports Writers Association Amateur Athlete of the Year.
Bonner was selected 5th overall in the 2009 WNBA Draft by the Phoenix Mercury. In her first regular season game with the Mercury, Bonner played 26 minutes and scored 16 points. October 9, 2009 as a rookie Bonner scored 13 points to contribute toward the 2009 championship. On September 12, 2014 Bonner won her second WNBA Championship, with 12 points, 9 rebounds and 3 assists.
During the WNBA offseason, Bonner has played in the Czech Republic for BK Brno, Spain for Baloncesto Rivas and CB Avenida, and Russia for Nadezhda Orenburg.