Girish Mahajan (Editor)

Dasolampanel

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ATC code
  
None

PubChem CID
  
51049972

UNII
  
1P85D6BE9K

Molar mass
  
377.825 g/mol

CAS Number
  
503294-13-1

ChemSpider
  
25948207

Formula
  
C17H20ClN5O3

Dasolampanel httpsuploadwikimediaorgwikipediacommonsthu

Dasolampanel (INN, USAN, code name NGX-426) is an orally bioavailable analog of tezampanel and thereby competitive antagonist of the AMPA and kainate receptors which was under development by Raptor Pharmaceuticals/Torrey Pines Therapeutics for the treatment of chronic pain conditions including neuropathic pain and migraine. It was developed as a follow-on compound to tezampanel, as tezampanel is not bioavailable orally and must be administered by intravenous injection, but ultimately neither drug was ever marketed.

References

Dasolampanel Wikipedia