DOx

Updated on Dec 19, 2024

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DOx is a chemical class of substituted amphetamine derivatives featuring methoxy groups at the 2- and 5- positions of the phenyl ring, and a substituent such as alkyl or halogen at the 4- position of the phenyl ring. The compounds of this class are potent and long-lasting psychedelic drugs, and act as highly selective 5-HT_2A, 5-HT_2B, and 5-HT_2C receptor partial agonists.

The DOx family includes the following members:

As well as the following members with additional substitutions:

2,5-Dimethoxy-4-methyl-α-ethylphenethylamine (Ariadne)

2,5-Dimethoxy-4,N-dimethylamphetamine (Beatrice)

2,5-Dimethoxy-3,4-methylenedioxyamphetamine (DMMDA)

2,5-Dimethoxy-3,4-dimethylamphetamine (Ganesha)

2,5-Dimethoxy-3,4-trimethylenylamphetamine (G-3)

2,5-Dimethoxy-3,4-tetramethylenylamphetamine (G-4)

2,5-Dimethoxy-3,4-norbornylamphetamine (G-5)

2,5-Dimethoxy-4-iodo-N,N-dimethylamphetamine (IDNNA)

2,5-dimethoxy-4-bromo-N-methylamphetamine (Methyl-DOB)

2,3,4,5-Tetramethoxyamphetamine (TA, TeMA)

References

DOx Wikipedia

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