Samiksha Jaiswal (Editor)

DNMT1

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Species
  
Human

Entrez
  
1786

Human
  
Mouse

Ensembl
  
ENSG00000130816

DNMT1

Aliases
  
DNMT1, ADCADN, AIM, CXXC9, DNMT, HSN1E, MCMT, m.HsaI, DNA (cytosine-5-)-methyltransferase 1

External IDs
  
OMIM: 126375 MGI: 94912 HomoloGene: 124071 GeneCards: DNMT1

DNA (cytosine-5)-methyltransferase 1 is an enzyme that in humans is encoded by the DNMT1 gene.

Contents

Function

DNA (cytosine-5-)-methyltransferase 1 has a role in the establishment and regulation of tissue-specific patterns of methylated cytosine residues. Aberrant methylation patterns are associated with certain human tumors and developmental abnormalities.

Interactions

DNMT1 has been shown to interact with UHRF1,:

  • DMAP1,
  • DNMT3A
  • DNMT3B,
  • HDAC2,
  • PCNA, and
  • RB1.

    • References

    DNMT1 Wikipedia
    (Text) CC BY-SA


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