Supriya Ghosh (Editor)

DEK (gene)

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Covid-19
Species  Human
Entrez  7913
Human  Mouse
Ensembl  ENSG00000124795
DEK (gene)
Aliases  DEK, D6S231E, DEK proto-oncogene
External IDs  MGI: 1926209 HomoloGene: 2593 GeneCards: DEK

The human DEK gene encodes the DEK protein.

Contents

Function

This gene encodes a protein with one SAP domain. The protein binds to cruciform and superhelical DNA and induces positive supercoils into closed circular DNA. It is also involved in splice site selection during mRNA processing. Chromosomal aberrations involving this region increased expression of this gene and the presence of antibodies against this protein are all associated with various diseases.

Interactions

DEK interacts with TFAP2A.

References

DEK (gene) Wikipedia


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