Aliases CCNK, CPR4, Cyclin K Human Mouse Ensembl ENSG00000090061 | Species Human Entrez 8812 | |
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External IDs MGI: 1276106 HomoloGene: 14748 GeneCards: CCNK | ||
Cyclin-K is a protein that in humans is encoded by the CCNK gene.
Contents
Function
The protein encoded by this gene is a member of the transcription cyclin family. These cyclins may regulate transcription through their association with and activation of cyclin-dependent kinases (CDK) that phosphorylate the C-terminal domain (CTD) of the large subunit of RNA polymerase II. This gene product may play a dual role in regulating CDK and RNA polymerase II activities.
Interactions
Cyclin K has been shown to interact with CDK9. Cyclin K also interacts with HIV nef protein.
References
Cyclin K Wikipedia(Text) CC BY-SA