There have been two baronetcies created in the Baronetage of England for members of the Culpeper family ( also known as Colpeper, Colepeper or Colepepper) of Kent and Sussex. Both are extinct.
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The baronets descended from the Culpepers of Bayhall, Pembury, Kent and from Sir Thomas Culpeper Castellan of Leeds Castle who died in 1321.
The Baronetcy of Culpeper of Preston Hall, Kent was created on 17 May 1627 for William Culpeper of Preston Hall, Aylesford, Kent. He served as High Sheriff of Kent in 1637. His grandson, the third Baronet, served as High Sheriff in 1704 and was Member of Parliament for Maidstone 1705–13 and 1715–1723. The Baronetcy was extinct on his death. The Kent estates passed to his sister and via her second marriage to the Milner family.
The Baronetcy of Culpeper of Wakehurst, Sussex was created on 20 September 1628 for William Culpeper, of Wakehurst, a descendant of the senior line of the Bayhill family. He was High Sheriff of Surrey and Sussex in 1634 and represented East Grinstead in the Parliament of 1640. He was succeeded in turn by two sons and his great grandson. The Baronetcy was extinct on the latter's death.
John Culpeper of Thoresby, Lincolnshire, a representative of a junior branch of the Bayhill family was raised to the Peerage in 1644 as Baron Culpeper.