Cooke is a surname. Notable people with the surname include:
Alan Cooke, British actor
Alexander Cooke (died 1614), English actor
Alfred Tyrone Cooke, of the Indo-Pakistani wars
Alistair Cooke KBE (1908–2004), journalist and broadcaster
Amos Starr Cooke (1810–1871), found of Royal School and Castle & Cooke in Hawaii
Anna Rice Cooke (1853–1934), patron of the arts and founder of the Honolulu Academy of Arts
Anthony Cooke (1505–1576), British scholar
Baden Cooke (born 1978), Australian cyclist
Barrie Cooke (born 1931), Irish painter
Bates Cooke, US Representative 1831-1833, and NY State Comptroller 1839–1841
Benjamin Cooke (1734–1793), British musician
Beryl Cooke (1906–2001), British actress
C. R. Cooke (Conrad Reginald Cooke, 1901–1996), English early Himalayan mountaineer
Charles Cooke (disambiguation), several people
Chauncey H. Cooke (1846–1919), American soldier in the U.S. Civil War
Christian Cooke (born 1986), English actor
Clarence Hyde Cooke (1876–1944), businessman in Hawaii
Dave Cooke, Canadian politician
Deryck Cooke (1919–1975), British musicologist
Doc Cook (Charles L. Cooke, 1891–1958), jazz bandleader
Edmund F. Cooke (1885–1967), US congressman from New York
Edward William Cooke (1811–1880), English maritime artist
Eric Edgar Cooke, murderer
Francis Cooke Passenger on the Mayflower
Francis Judd Cooke (1910–1995), American composer
Geoff Cooke (disambiguation), several people
George Cooke (disambiguation), several people
H. Basil S. Cooke (born 1915), Canadian paleontologist
Hope Cooke, Queen of Sikkim
Sir James Douglas Cooke (1879–1949), MP for Hammersmith South
James J. Cooke, American historian, author, academic and soldier
James W. Cooke, American naval officer
Janet Cooke (born 1954), American journalist, won a Pulitzer Prize for a fabricated story
Jay Cooke (1821–1905), American financier, notable for financing Union effort in Civil War and Northern Pacific Railway
Jennifer Cooke, actress
John Cooke (disambiguation), several people
Joseph Platt Cooke (1730–1816), in American Revolutionary War
Keith Cooke, actor
L. J. Cooke (Louis Joseph Cooke, 1868–1943), first men's basketball coach at the University of Minnesota
Lawrence H. Cooke (1914–2000), Chief Judge of New York Court of Appeals 1979–1984
Martin Cooke (disambiguation), several people
Matt Cooke, hockey player
Mel Cooke (1934–2013), New Zealand rugby league footballer
Mordecai Cubitt Cooke (1825–1914), British botanist
Nicole Cooke (born 1983), British cyclist
Peter Cooke (Scouting)
Philip St. George Cooke (1809–1895), 19th century US cavalry officer
Pinny Cooke (1923–2004), New York politician, assemblywoman from Rochester
Robin Cooke, Baron Cooke of Thorndon, New Zealand judge
Sam Cooke (1931–1964), American singer/songwriter
Samuel Nathaniel Cooke (S. N. Cooke) (born 1883), English architect
Sidney Cooke (born 1927), paedophile and child killer
Steve Cooke (born 1970), baseball player
Terence Cooke (1921–1983), Cardinal, and Archbishop of New York
Thomas Cooke (disambiguation), several people
Walter E. Cooke (1910–1982), New York politician
Walter H. Cooke (1838–1909), American recipient of the Medal of Honor
Weldon B. Cooke (1884–1914), American pioneer aviator killed in crash
Wells Cooke (1858–1916), American ornithologist
William Cooke (disambiguation), several people