Known for CATH database Name Christine Orengo | Fields Bioinformatics | |
Born Christine Anne Orengo
June 22, 1955 (age 68) ( 1955-06-22 ) Institutions National Institute for Medical Research (NIMR)
University College London (UCL) Thesis A study of the redox properties of haem in proteins and model systems (1984) Doctoral students Giorgos Baskozos
Sayoni Das
Natalie Dawson
Su Datt Lam
Sonja Lehtinen
Ian Sillitoe Notable awards European Molecular Biology Organization (2014) Alma mater University of Bristol, University of Aberdeen, University College London Institution National Institute for Medical Research, University College London | ||
Exploiting structural and comparative genomics to reveal protein functions
Christine Anne Orengo is a Professor of Bioinformatics at University College London (UCL) known for her work on protein structure, particularly the CATH database.
Contents
- Exploiting structural and comparative genomics to reveal protein functions
- Education
- Career
- Research
- Awards and honours
- References
Education
Orengo studied Chemical Physics at the University of Bristol where she was awarded a Bachelor of Science degree. She continued her studies at the University of Aberdeen where she was awarded a Master of Science degree in Medical Physics in 1977 for research on the disruption of iron metabolism in laboratory rats with Yoshida sarcomas. She was awarded a PhD for research on the redox properties of haem in proteins in 1984 from UCL.
Career
Following her PhD, Orengo worked in industry before being appointed a postdoctoral researcher at the National Institute for Medical Research (NIMR) in Mill Hill where she worked until 1990. She joined the Department of Biochemistry and Molecular Biology at UCL and in 1995 and was awarded a Medical Research Council (MRC) Senior Fellowship in Bioinformatics. She was promoted to Professor of Bioinformatics in 2002.
Research
Orengo's research analyses genes, proteins and biological systems using computational methods to classify proteins into evolutionary families. This work has been funded by the Medical Research Council (MRC) and the Biotechnology and Biological Sciences Research Council (BBSRC).
Orengo is co-editor with David Jones and Janet Thornton of the textbook Bioinformatics: Genes, Proteins and Computers. As of 2015, according to Google Scholar and Scopus her most cited work has been published in Nature, Nucleic Acids Research, Structure and the Journal of Molecular Biology.
Awards and honours
Orengo was elected a member of the European Molecular Biology Organization (EMBO) in 2014.