Trade names Evoxac MedlinePlus a608025 Routes ofadministration By mouth (capsules) Molar mass 199.3131 g/mol | AHFS/Drugs.com Monograph Pregnancycategory C ATC code N07AX03 (WHO) CAS ID 107233-08-9 | |
 | ||
Cevimeline (trade name Evoxac) is a parasympathomimetic and muscarinic agonist, with particular effect on M1 and M3 receptors. It is used in the treatment of dry mouth and especially associated with Sjögren's syndrome.
Contents
Mechanism of action
By activating the M3 receptors of the parasympathetic nervous system, cevimeline stimulates secretion by the salivary glands, thereby alleviating dry mouth.
Side effects
Known side effects include nausea, vomiting, diarrhea, excessive sweating, rash, headache, runny nose, cough, drowsiness, hot flashes, blurred vision, and difficulty sleeping.
Contraindications include asthma and angle closure glaucoma.
References
Cevimeline Wikipedia(Text) CC BY-SA