Cellosaurus

Cellosaurus is an on-line knowledge resource on cell lines. Its scope includes immortalised cell lines, naturally immortal cell lines (example: embryonic stem cells) and finite life cell lines when those are distributed and used widely. The Cellosaurus provides a wealth of manually curated information; for each cell line it lists a recommended name, synonyms and the species of origin. Other types of information include standardised disease terminology (for cancer or genetic disorder cell lines), the transformant used to immortalise a cell line, transfected or knocked-out genes, microsatellite instability, doubling time, web links, publication references and cross-references to more than 61 different databases, cell collections and other relevant resources.

Contents

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• References

Since many cell lines used in research have been misidentified or contaminated, the Cellosaurus keeps track of problematic cell lines, including all those listed in the International Cell Line Authentication Committee (ICLAC) tables.

For human cell lines, it provides short tandem repeat (STR) profile information, which is critical to the important process of cell line authentication.

It is developed by Amos Bairoch at the CALIPHO group of the Swiss Institute of Bioinformatics (SIB).