MedlinePlus a601206 CAS Number 56796-20-4 DrugBank DB00274 | ATC code J01DC09 (WHO) PubChem CID 42008 Molar mass 471.538 g/mol | |
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AHFS/Drugs.com International Drug Names | ||
Cefmetazole is a cephamycin antibiotic, usually grouped with the second-generation cephalosporins.
Contents
- Medical vocabulary what does cefmetazole mean
- Adverse effects
- Spectrum of bacterial susceptibility
- References
Medical vocabulary what does cefmetazole mean
Adverse effects
The chemical structure of cefmetazole, like that of several other cephalosporins, contains an N-methylthiotetrazole (NMTT or 1-MTT) side chain. As the antibiotic is broken down in the body, it releases free NMTT, which can cause hypoprothrombinemia (likely due to inhibition of the enzyme vitamin K epoxide reductase) and a reaction with ethanol similar to that produced by disulfiram, due to inhibition of aldehyde dehydrogenase.
Spectrum of bacterial susceptibility
Cefmetazole is a broad-spectrum cephalosporin antimicrobial and has been effective in treating bacteria responsible for causing urinary tract and skin infections. The following represents MIC susceptibility data for a few medically significant microorganisms.