Ezeta was born in San Salvador on June 14, 1852 (Source 1).
On June 22, 1890, Ezeta travelled to the White House of the Incumbent President, General Francisco Menéndez, and started an uprising that overthrew Menendéz (Source 1). Menendéz died soon after this (Source 1). On March 1, 1891, Ezeta formally took office as the President of El Salvador (Source 1).
Ezeta oversaw El Salvador's relative political stability at a time when the neighboring republics of Honduras and Guatemala were at war, but he soon lost favour with the landowners and was overthrown in another coup on June 9, 1894 by Rafael Antonio Gutiérrez with assistance from Nicaragua, Guatemala and Honduras (Source 1). He fled to Panama, and then travelled to Europe as there was a warrant for his death; he then returned to Central America and then settled in Mazatlan, Mexico, where he died on March 21, 1903, aged 50 (Source 1). His remains are buried at Angela Peralta Cemetery of this city.