Formula C20H28O3 | Molar mass 316.439 g/mol | |
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Cafestol is a diterpene molecule present in coffee.
Contents
- Global and china cafestol industry cas 469 83 0 2019 forecasts and analysis
- Potential biological activity
- References
A typical bean of Coffea arabica contains about 0.4-0.7% cafestol by weight. Cafestol is present in highest quantity in unfiltered coffee drinks such as French press coffee or Turkish coffee/Greek coffee. In filtered coffee drinks such as drip brewed coffee, it is present in only negligible amounts.
Studies have shown that regular consumption of boiled coffee increases serum cholesterol by 8% in men and 10% in women. For those drinking filter coffee, the effect was only significant for women.
Global and china cafestol industry cas 469 83 0 2019 forecasts and analysis
Potential biological activity
Cafestol has also shown anticarcinogenic properties in rats. Cafestol may act as an agonist ligand for the nuclear receptor farnesoid X receptor and pregnane X receptor, blocking cholesterol homeostasis. Cafestol also has neuroprotective effects in a Drosophila fruit fly model of Parkinson's disease.