Species Human Entrez 1013 | Human Mouse Ensembl ENSG00000129910 | |
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Aliases CDH15, CDH14, CDH3, CDHM, MCAD, MRD3, cadherin 15 External IDs MGI: 106672 HomoloGene: 3622 GeneCards: CDH15 | ||
Cadherin-15 is a protein that in humans is encoded by the CDH15 gene.
Contents
Function
This gene is a member of the cadherin superfamily of genes, encoding calcium-dependent intercellular adhesion glycoproteins. Cadherins consist of an extracellular domain containing 5 cadherin domains, a transmembrane region, and a conserved cytoplasmic domain. Transcripts from this particular cadherin are expressed in myoblasts and upregulated in myotubule-forming cells. The protein is thought to be essential for the control of morphogenetic processes, specifically myogenesis, and may provide a trigger for terminal muscle cell differentiation.
Interactions
CDH15 has been shown to interact with ARVCF.
References
CDH15 Wikipedia(Text) CC BY-SA